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首页> Laboratory investigation; a journal of technical methods and pathology> SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition.

SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition.

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作者： Laura,Lopez-Sanz ^[1] ; Susana,Bernal ^[2] ; Carlota,Recio ^[3] ; Iolanda,Lazaro ^[1] ; Ainhoa,Oguiza ^[2] ; Ana,Melgar ^[3] ; Luna,Jimenez-Castilla ^[1] ; Jesus,Egido ^[2] ; Carmen,Gomez-Guerrero ^[3]

作者单位： Renal and Vascular Inflammation Group, Fundacion Jimenez Diaz University Hospital-Health Research Institute (FIIS-FJD), Autonoma University of Madrid (UAM), Madrid, Spain. ^[1] Division of Nephrology and Hypertension, Fundacion Jimenez Diaz University Hospital-Health Research Institute (FIIS-FJD), Autonoma University of Madrid (UAM), Madrid, Spain. ^[2] Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain. ^[3] Renal and Vascular Inflammation Group, Fundacion Jimenez Diaz University Hospital-Health Research Institute (FIIS-FJD), Autonoma University of Madrid (UAM), Madrid, Spain. cgomez@fjd.es. ^[4] Division of Nephrology and Hypertension, Fundacion Jimenez Diaz University Hospital-Health Research Institute (FIIS-FJD), Autonoma University of Madrid (UAM), Madrid, Spain. cgomez@fjd.es. ^[5] Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain. cgomez@fjd.es. ^[6]

主题词动物(Animals);抗氧化剂(Antioxidants);主动脉(Aorta);糖尿病血管病变(Diabetic Angiopathies);糖尿病肾病(Diabetic Nephropathies);肾(Kidney);男(雄)性(Male);小鼠(Mice);氧化性应激(Oxidative Stress);多肽模拟物(Peptidomimetics);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);活性氧(Reactive Oxygen Species);STAT1转录因子(STAT1 Transcription Factor)

DOI 10.1038/s41374-018-0043-6

PMID 29540859

发布时间 2023-02-16

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Laboratory investigation; a journal of technical methods and pathology

Laboratory investigation; a journal of technical methods and pathology

2018年98卷10期

1276-1290页

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Laboratory investigation; a journal of technical methods and pathology

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Laboratory investigation; a journal of technical methods and pathology

2018年98卷10期

1276-1290页

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