Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.

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第一作者： Chengzheng,Han

第一单位： Clinic of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, P.R. China.

作者： Chengzheng,Han ^[1] ; Guozheng,Xing ^[2] ; Mengying,Zhang ^[3] ; Min,Zhong ^[3] ; Zhen,Han ^[4] ; Chiyi,He ^[4] ; Xiaoping,Liu ^[5]

作者单位： Clinic of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, P.R. China. ^[1] School of Management, Science and Engineering, Anhui University of Technology, Ma'anshan, Anhui 243032, P.R. China. ^[2] Department of Central Laboratory, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, P.R. China. ^[3] Department of Gastroenterology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui 241001, P.R. China. ^[4] College of Pharmacy, Wannan Medical College, Wuhu, Anhui 241001, P.R. China. ^[5]

关键词 RAC-α serine/threonine-protein kinase human colon cancer cells mechanistic target of rapamycin p70 S6 kinase phosphatidylinositol 3 kinase wogonoside

DOI 10.3892/ol.2018.7852

PMID 29541215

发布时间 2020-10-01

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