换一批In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but Not to Ca2+ Handling or β-Adrenoceptor Signaling.
第一作者：
Frederik,Flenner
第一单位：
From the Department of Experimental Pharmacology and Toxicology (F. Flenner, M.N., F. Friedrich, T.C.) Institute of Experimental Cardiovascular Research, Cardiovascular Research Center (S.S., V.N.), University Hospital Hamburg-Eppendorf, Hamburg, Germany Department of Pharmacology and Toxicology (N.A., U.R., T.C.) Department of Anesthesiology and Intensive Care Medicine (N.A., T.K., S.N.S.), Medical Faculty Carl Gustav Carus, Dresden, Germany Department of Anesthesiology and Intensive Care Medicine, University of Leipzig, Germany (S.N.S.) the German Center for Cardiovascular Research, partner site Hamburg/Kiel/Lübeck, Germany (F. Flenner, S.S., F. Friedrich, V.N., T.C.) Current position: Institute for Experimental Cardiovascular Medicine, University Heart Center, Medical Center, and Faculty of Medicine, University of Freiburg, Freiburg, Germany (U.R.).
作者：
医学主题词
麻醉药, 局部(Anesthetics, Local);动物(Animals);布比卡因(Bupivacaine);钙(Calcium);细胞, 培养的(Cells, Cultured);剂量效应关系, 药物(Dose-Response Relationship, Drug);豚鼠(Guinea Pigs);男(雄)性(Male);小鼠(Mice);心肌收缩(Myocardial Contraction);肌细胞, 心脏(Myocytes, Cardiac);器官培养技术(Organ Culture Techniques);受体, 肾上腺素能β(Receptors, Adrenergic, beta)
DOI
10.1097/ALN.0000000000002180
PMID
29547406
发布时间
2019-08-20
- 浏览8
Anesthesiology
1175-1186页
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