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CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5.

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第一作者： María Victoria,Repetto

第一单位： Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires (UBA), C1428EGA Buenos Aires, Argentina; CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Buenos Aires C1428EHA, Argentina.

作者： María Victoria,Repetto ^[1] ; Matthew J,Winters ^[2] ; Alan,Bush ^[1] ; Wolfgang,Reiter ^[3] ; David Maria,Hollenstein ^[3] ; Gustav,Ammerer ^[3] ; Peter M,Pryciak ^[4] ; Alejandro,Colman-Lerner ^[5]

作者单位： Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires (UBA), C1428EGA Buenos Aires, Argentina; CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Buenos Aires C1428EHA, Argentina. ^[1] Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. ^[2] Department for Biochemistry, Max F. Perutz Laboratories, University of Vienna, Vienna 1030, Austria. ^[3] Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: peter.pryciak@umassmed.edu. ^[4] Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires (UBA), C1428EGA Buenos Aires, Argentina; CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Buenos Aires C1428EHA, Argentina. Electronic address: colman-lerner@fbmc.fcen.uba.ar. ^[5]

关键词 Cdc28 Cks1 Cln2 G protein Ste4 cyclin mating pheromone signal transduction start