The transgenic chicken derived anti-CD20 monoclonal antibodies exhibits greater anti-cancer therapeutic potential with enhanced Fc effector functions.

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第一作者： Young Min,Kim

第一单位： Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea.

作者： Young Min,Kim ^[1] ; Jin Se,Park ^[1] ; Sang Kyung,Kim ^[1] ; Kyung Min,Jung ^[1] ; Young Sun,Hwang ^[1] ; Mookyoung,Han ^[1] ; Hong Jo,Lee ^[1] ; Hee Won,Seo ^[2] ; Jeong-Yong,Suh ^[1] ; Beom Ku,Han ^[3] ; Jae Yong,Han ^[4]

作者单位： Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea. ^[1] Samsung Bioepis Co., Ltd, 107, Cheomdan-daero, Yeonsu-gu, Incheon, 21987, South Korea. ^[2] Optipharm Inc, 63, Osongsaengmyeong 6-ro, Cheongju-si, Chungcheongbku-do, South Korea. ^[3] Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, South Korea; Institute for Biomedical Sciences, Shinshu University, Minamiminowa, Nagano, 399-4598, Japan. Electronic address: jaehan@snu.ac.kr. ^[4]

关键词 Bioreactor Fc effector functions N-glycan Therapeutic antibody Transgenic chicken