IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling.

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作者： Tomasz,Herjan ^[1] ; Lingzi,Hong ^[2] ; Jodi,Bubenik ^[1] ; Katarzyna,Bulek ^[3] ; Wen,Qian ^[1] ; Caini,Liu ^[4] ; Xiao,Li ^[1] ; Xing,Chen ^[1] ; Hui,Yang ^[5] ; Suidong,Ouyang ^[1] ; Hao,Zhou ^[1] ; Junjie,Zhao ^[1] ; Kommireddy,Vasu ^[1] ; Eric,Cockman ^[1] ; Mark,Aronica ^[3] ; Kewal,Asosingh ^[3] ; Donny D,Licatalosi ^[6] ; Jun,Qin ^[6] ; Paul L,Fox ^[7] ; Thomas A,Hamilton ^[8] ; Donna,Driscoll ^[3] ; Xiaoxia,Li ^[1]

作者单位： Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. ^[1] Department of General Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland. ^[2] Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. ^[3] Department of Immunology, Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Krakow, Poland. ^[4] Department of Genetics, Stanford University School of Medicine, Stanford, California, USA. ^[5] Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA. ^[6] Center for RNA Molecular Biology, Department of Biochemistry, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA. ^[7] Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. ^[8] Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. lix@ccf.org. ^[9]