首页> Xenobiotica; the fate of foreign compounds in biological systems> Evaluation of interconversion pharmacokinetics of 16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide - a novel HMG-CoA reductase inhibitor and its acid metabolite using multi-compartmental pharmacokinetic model in mice.

Evaluation of interconversion pharmacokinetics of 16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide - a novel HMG-CoA reductase inhibitor and its acid metabolite using multi-compartmental pharmacokinetic model in mice.

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第一作者： Tulsankar Sachin,Laxman

第一单位： a Pharmacokinetics & Metabolism Division , CSIR-Central Drug Research Institute , Lucknow , India.;b Academy of Scientific and Innovative Research (AcSIR) , New Delhi , India.

作者： Tulsankar Sachin,Laxman ^[1] ; Santosh Kumar,Puttervu ^[1] ; Anjali,Mishra ^[2] ; Sarvesh,Verma ^[2] ; S P,Singh ^[3] ; K V,Sashidhara ^[3] ; C M,Marandi ^[4] ; Shivani,Saxena ^[4] ; Manoj K,Yadav ^[3] ; Rabi S,Bhatta ^[5]

作者单位： a Pharmacokinetics & Metabolism Division , CSIR-Central Drug Research Institute , Lucknow , India.;b Academy of Scientific and Innovative Research (AcSIR) , New Delhi , India. ^[1] a Pharmacokinetics & Metabolism Division , CSIR-Central Drug Research Institute , Lucknow , India. ^[2] c Medicinal & Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow , India. ^[3] d Department of Pharmaceutics , National Institute of Pharmaceutical Education and Research (NIPER) , Rae Bareli , India. ^[4] a Pharmacokinetics & Metabolism Division , CSIR-Central Drug Research Institute , Lucknow , India.;d Department of Pharmaceutics , National Institute of Pharmaceutical Education and Research (NIPER) , Rae Bareli , India. ^[5]

关键词 4655K-09 interconversion parameters lactone–acid interconversion multi-compartmental interconversion model