Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice.

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作者： F,Cathomas ^[1] ; D,Azzinnari ^[2] ; G,Bergamini ^[1] ; H,Sigrist ^[3] ; M,Buerge ^[1] ; V,Hoop ^[3] ; B,Wicki ^[1] ; L,Goetze ^[1] ; S,Soares ^[1] ; D,Kukelova ^[4] ; E,Seifritz ^[1] ; S,Goebbels ^[1] ; K-A,Nave ^[1] ; M S,Ghandour ^[1] ; C,Seoighe ^[2] ; T,Hildebrandt ^[5] ; G,Leparc ^[5] ; H,Klein ^[6] ; E,Stupka ^[7] ; B,Hengerer ^[8] ; C R,Pryce ^[9]

作者单位： Preclinical Laboratory for Translational Research into Affective Disorders, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland. ^[1] Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland. ^[2] Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland. ^[3] Institute of Human Movement Sciences and Sport, ETH Zurich, Zurich, Switzerland. ^[4] Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany. ^[5] Center of Neurochemistry, University of Strasbourg, UMR 7357, Strasbourg, France. ^[6] Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia. ^[7] School of Mathematics, Statistics & Applied Mathematics, National University of Ireland, Galway, Ireland. ^[8] Target Discovery Germany, Boehringer Ingelheim Pharma GmbH & Co. KG., Biberach, Germany. ^[9] CNS Diseases Research Germany, Boehringer Ingelheim Pharma GmbH & Co. KG., Biberach, Germany. ^[10]

关键词 amygdala cell deconvolution depression differential gene expression gray and white matter inflammation mouse myelin transcriptome myelin-axon integrity oligodendrocyte social stress