Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.-论文-万方医学网

作者： Tali,Czarnowicki ^[1] ; Anders B,Dohlman ^[2] ; Kunal,Malik ^[3] ; Diane,Antonini ^[4] ; Robert,Bissonnette ^[5] ; Tom C,Chan ^[6] ; Lisa,Zhou ^[6] ; Huei-Chi,Wen ^[6] ; Yeriel,Estrada ^[6] ; Hui,Xu ^[6] ; Catherine,Bryson ^[4] ; Jie,Shen ^[7] ; Deepak,Lala ^[4] ; Avi,Ma'ayan ^[2] ; Gerard,McGeehan ^[4] ; Richard,Gregg ^[4] ; Emma,Guttman-Yassky ^[8]

作者单位： Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York. ^[1] Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, BD2K-LINCS Data Coordination and Integration Center, Icahn School of Medicine at Mount Sinai School, New York, New York. ^[2] Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; College of Medicine, SUNY Downstate, Brooklyn, New York. ^[3] Vitae Pharmaceuticals Inc, an Allergan affiliate, Irvine, California. ^[4] Innovaderm Research Inc, Montreal, Quebec, Canada. ^[5] Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York. ^[6] Allergan plc, Irvine, California. ^[7] Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York. Electronic address: emma.guttman@mountsinai.org. ^[8]

主题词 ATP结合匣式转运子(ATP-Binding Cassette Transporters);投药, 皮肤(Administration, Cutaneous);成年人(Adult);消炎药(Anti-Inflammatory Agents);生物转运(Biological Transport);皮炎, 特应性(Dermatitis, Atopic);双盲法(Double-Blind Method);表皮(Epidermis);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);免疫因子类(Immunologic Factors);白细胞介素6(Interleukin-6);中间丝蛋白质类(Intermediate Filament Proteins);角蛋白16(Keratin-16);男(雄)性(Male);膜蛋白质类(Membrane Proteins);中年人(Middle Aged);RNA, 信使(RNA, Messenger);疾病严重程度指数(Severity of Illness Index);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);治疗结果(Treatment Outcome)

DOI 10.1016/j.anai.2018.03.013

PMID 29567358

发布时间 2021-12-04

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Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.

Annals of allergy, asthma & immunology

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Annals of allergy, asthma & immunology

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Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.

Annals of allergy, asthma & immunology

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Annals of allergy, asthma & immunology

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