Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.

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作者： Kentaro,Oniki ^[1] ; Takehisa,Watanabe ^[2] ; Miku,Kudo ^[1] ; Tomoko,Izuka ^[1] ; Tatsumasa,Ono ^[1] ; Kazuki,Matsuda ^[1] ; Yuki,Sakamoto ^[1] ; Katsuya,Nagaoka ^[2] ; Tadashi,Imafuku ^[3] ; Yu,Ishima ^[4] ; Hiroshi,Watanabe ^[3] ; Toru,Maruyama ^[3] ; Koji,Otake ^[5] ; Yasuhiro,Ogata ^[2] ; Junji,Saruwatari ^[1]

作者单位： Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. ^[1] Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. ^[2] Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. ^[3] Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan. ^[4] Japanese Red Cross Kumamoto Health Care Center, Kumamoto, Japan. ^[5] Center for Clinical Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. ^[6]

主题词脂联素(Adiponectin);老年人(Aged);人体质量指数(Body Mass Index);体重(Body Weight);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);谷胱甘肽转移酶(Glutathione Transferase);人类(Humans);日本(Japan);纵向研究(Longitudinal Studies);男(雄)性(Male);普查(Mass Screening);中年人(Middle Aged);非线性动力学(Nonlinear Dynamics);肥胖症(Obesity);多态性, 单核苷酸(Polymorphism, Single Nucleotide);患病率(Prevalence);回顾性研究(Retrospective Studies)

DOI 10.1002/psp4.12292

PMID 29569850

发布时间 2019-09-23

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CPT: pharmacometrics & systems pharmacology

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2018年7卷6期

384-393页

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Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.

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Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.

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