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Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy.

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第一作者： Fan,Niu

第一单位： Center for Translational Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.

作者： Fan,Niu ^[1] ; Jin,Yan ^[2] ; Bohan,Ma ^[1] ; Shichao,Li ^[1] ; Yongping,Shao ^[1] ; Pengcheng,He ^[3] ; Wanggang,Zhang ^[4] ; Wangxiao,He ^[5] ; Peter X,Ma ^[6] ; Wuyuan,Lu ^[7]

作者单位： Center for Translational Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. ^[1] Center for Bioengineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. ^[2] Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ^[3] Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ^[4] Center for Translational Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. Electronic address: hewangxiao@stu.edu.xjtu.cn. ^[5] Center for Bioengineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China; Department of Biologic and Materials Sciences, Department of Biomedical Engineering, Macromolecular Science and Engineering Center, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: mapx@umich.edu. ^[6] Center for Translational Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China; Institute of Human Virology and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: wlu@ihv.umaryland.edu. ^[7]

关键词 Acute myeloid leukemia CD33 antibody Lanthanide-doped theranostic nanoparticles Peptide delivery p53