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首页> Gynecologic oncology> Helicase POLQ-like (HELQ) as a novel indicator of platinum-based chemoresistance for epithelial ovarian cancer.

Helicase POLQ-like (HELQ) as a novel indicator of platinum-based chemoresistance for epithelial ovarian cancer.

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作者： Jing,Long ^[1] ; Jun-You,Zhu ^[1] ; Yong-Bin,Liu ^[2] ; Kun,Fu ^[1] ; Yan,Tian ^[1] ; Pei-Yao,Li ^[3] ; Wen-Qing,Yang ^[3] ; Si-Yu,Yang ^[3] ; Ji-Ye,Yin ^[4] ; Gang,Yin ^[5] ; Yu,Zhang ^[6]

作者单位： Obstetrics and Gynecology Department, Xiangya Hospital, Central South University, China. ^[1] Institution of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, China. ^[2] Obstetrics and Gynecology Department, Xiangya Hospital, Central South University, China; Hunan Provincial Gynecological Cancer Diagnosis and Treatment Engineering Research Center, China. ^[3] Institution of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, China; Hunan Provincial Gynecological Cancer Diagnosis and Treatment Engineering Research Center, China. ^[4] Department of Pathology, School of Basic Medical Science, Central South University, China. ^[5] Obstetrics and Gynecology Department, Xiangya Hospital, Central South University, China; Hunan Provincial Gynecological Cancer Diagnosis and Treatment Engineering Research Center, China. Electronic address: cszhangyu@126.com. ^[6]

关键词 Chemoresistance DNA repair Epithelial ovarian cancer HELQ NER

主题词抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);顺铂(Cisplatin);DNA解旋酶类(DNA Helicases);DNA修复(DNA Repair);无病生存(Disease-Free Survival);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);基因敲低技术(Gene Knockdown Techniques);人类(Humans);免疫组织化学(Immunohistochemistry);中年人(Middle Aged);肿瘤分期(Neoplasm Staging);肿瘤, 腺和上皮(Neoplasms, Glandular and Epithelial);卵巢肿瘤(Ovarian Neoplasms);存活率(Survival Rate)

DOI 10.1016/j.ygyno.2018.03.006

PMID 29572031

发布时间 2021-01-14

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Gynecologic oncology

Gynecologic oncology

2018年149卷2期

341-349页

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2018年149卷2期

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