Repression of adenosine triphosphate-binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury.

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作者： Jin A,Shin ^[1] ; Sae Im,Jeong ^[2] ; Hye Won,Kim ^[1] ; Gyeonghui,Jang ^[1] ; Dong-Ryeol,Ryu ^[3] ; Young-Ho,Ahn ^[4] ; Ji Ha,Choi ^[1] ; Youn-Hee,Choi ^[5] ; Eun-Mi,Park ^[6]

作者单位： Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. ^[1] Department of Pharmacology, Tissue Injury Defense Research Center, School of Medicine, Ewha Womans University, Seoul, Republic of Korea. ^[2] Department of Internal Medicine, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. ^[3] Department of Molecular Medicine, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. ^[4] Department of Physiology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. ^[5] Department of Pharmacology, Tissue Injury Defense Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea. Electronic address: empark@ewha.ac.kr. ^[6]

关键词 ABCG2 Brain endothelial cell Estrogen Glutathione Ischemic stroke Neuroprotection