Immunogenicity and safety of the quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in splenectomized or hyposplenic children and adolescents: Results of a phase III, open, non-randomized study.-论文-万方医学网

作者： Nicola P,Klein ^[1] ; Tomas,Habanec ^[2] ; Pavel,Kosina ^[3] ; Nirmish R,Shah ^[4] ; Devayani,Kolhe ^[5] ; Jacqueline M,Miller ^[6] ; Marjan,Hezareh ^[7] ; Marie,Van der Wielen ^[8]

作者单位： Kaiser Permanente Vaccine Study Center, 1 Kaiser Plaza, 16th Floor, Oakland, CA 94612, United States. Electronic address: Nicola.Klein@kp.org. ^[1] Clinic of Children's Infectious Diseases, Černopolní 212/9, 662 63 Brno, Czech Republic. Electronic address: habanec.tomas@fnbrno.cz. ^[2] Department of Infectious Diseases, University Hospital, Charles University in Prague, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. Electronic address: Kosinpav@seznam.cz. ^[3] Department of Medicine, Duke University School of Medicine, Durham, NC 27703, United States. Electronic address: nirmish.shah@duke.edu. ^[4] GSK, 5, Embassy Links, SRT Road, Opp to Accenture, Cunningham Road, Vasanth Nagar, Bangalore, Karnataka 560052, India. Electronic address: devayani2000in@yahoo.co.in. ^[5] GSK, 14200 Shady Grove Road, Rockville, MD 20850, United States. Electronic address: jacqueline.m.miller@gsk.com. ^[6] Chiltern International for GSK, Avenue Fleming 20 (W23), 1300 Wavre, Belgium. Electronic address: mhezareh@yahoo.com. ^[7] GSK, Avenue Fleming 20 (W23), 1300 Wavre, Belgium. Electronic address: marie.x.van-der-wielen@gsk.com. ^[8]

主题词青少年(Adolescent);动物(Animals);抗体, 细菌(Antibodies, Bacterial);抗体生成(Antibody Formation);血液杀菌作用(Blood Bactericidal Activity);儿童(Child);儿童, 学龄前(Child, Preschool);队列研究(Cohort Studies);补体系统蛋白质类(Complement System Proteins);女(雌)性(Female);人类(Humans);发病率(Incidence);男(雄)性(Male);脑膜炎双球菌感染(Meningococcal Infections);脑膜炎双球菌菌苗(Meningococcal Vaccines);脑膜炎奈瑟球菌(Neisseria meningitidis);兔(Rabbits);破伤风类毒素(Tetanus Toxoid);接种(Vaccination);疫苗, 结合(Vaccines, Conjugate)

DOI 10.1016/j.vaccine.2018.02.085

PMID 29576307

发布时间 2018-09-11

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Immunogenicity and safety of the quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in splenectomized or hyposplenic children and adolescents: Results of a phase III, open, non-randomized study.

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Immunogenicity and safety of the quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in splenectomized or hyposplenic children and adolescents: Results of a phase III, open, non-randomized study.

Vaccine

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