Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
第一作者:
M,Baretti
第一单位:
a Medical Oncology and Hematology Unit, Humanitas Cancer Center, Humanitas Clinical and Research Center , Rozzano (Milan) , Italy.
作者:
医学主题词
老年人(Aged);抗肿瘤药(Antineoplastic Agents);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);结直肠肿瘤(Colorectal Neoplasms);女(雌)性(Female);人类(Humans);免疫组织化学(Immunohistochemistry);肝肿瘤(Liver Neoplasms);分子靶向治疗(Molecular Targeted Therapy);突变(Mutation);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));体层摄影术, X线计算机(Tomography, X-Ray Computed);治疗结果(Treatment Outcome)
DOI
10.1080/15384047.2018.1450117
PMID
29580164
发布时间
2020-09-30
- 浏览7
Cancer biology & therapy
659-663页
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