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首页> Journal of virology> Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal <i>Ex Vivo</i>.

Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal <i>Ex Vivo</i>.

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作者： Carolina,Garrido ^[1] ; Maria,Abad-Fernandez ^[2] ; Marina,Tuyishime ^[1] ; Justin J,Pollara ^[3] ; Guido,Ferrari ^[4] ; Natalia,Soriano-Sarabia ^[4] ; David M,Margolis ^[4]

作者单位： UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. ^[1] Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. ^[2] Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. ^[3] Department of Surgery and Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, USA. ^[4] UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA dmargo@med.unc.edu. ^[5] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. ^[6]

关键词 ADCC HIV HIV eradication IL-15 NK cell SAHA VOR human immunodeficiency virus immune function immunotherapy interleukins kick and kill latency reversal natural killer cells shock and kill vorinostat

主题词成年人(Adult);抗逆转录病毒药(Anti-Retroviral Agents);抗体依赖细胞细胞毒性(Antibody-Dependent Cell Cytotoxicity);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞, 培养的(Cells, Cultured);HIV感染(HIV Infections);HIV-1(HIV-1);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);人类(Humans);羟肟酸类(Hydroxamic Acids);免疫疗法(Immunotherapy);干扰素γ(Interferon-gamma);白细胞介素15(Interleukin-15);杀伤细胞, 天然(Killer Cells, Natural);淋巴细胞活化(Lymphocyte Activation);受体, 自然杀伤细胞(Receptors, Natural Killer Cell);病毒潜伏期(Virus Latency)

DOI 10.1128/JVI.00235-18

PMID 29593039

发布时间 2019-10-25

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Journal of virology

Journal of virology

2018年92卷12期

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