Bioimaging of metallothioneins in ocular tissue sections by laser ablation-ICP-MS using bioconjugated gold nanoclusters as specific tags.

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作者： María,Cruz-Alonso ^[1] ; Beatriz,Fernandez ^[2] ; Lydia,Álvarez ^[3] ; Héctor,González-Iglesias ^[4] ; Heike,Traub ^[5] ; Norbert,Jakubowski ^[6] ; Rosario,Pereiro ^[7]

作者单位： Deparment of Physical and Analytical Chemistry, University of Oviedo, Julian Claveria 8, 33006, Oviedo, Spain. ^[1] Deparment of Physical and Analytical Chemistry, University of Oviedo, Julian Claveria 8, 33006, Oviedo, Spain. fernandezbeatriz@uniovi.es. ^[2] Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, Spain. fernandezbeatriz@uniovi.es. ^[3] Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, Spain. ^[4] Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, Spain. hgonzalez@fio.as. ^[5] Instituto Oftalmológico Fernández-Vega, Avda. Dres. Fernández-Vega, 34, 33012, Oviedo, Spain. hgonzalez@fio.as. ^[6] Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstaetter-Strasse 11, 12489, Berlin, Germany. ^[7]

关键词 Bioconjugation Carbodiimide crosslinking Fluorescence Immunohistochemistry Laser ablation Mass spectrometry Metal nanoclusters Protein imaging Thin tissue sections