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HLA-inferred extended haplotype disparity level is more relevant than the level of HLA mismatch alone for the patients survival and GvHD in T cell-replate hematopoietic stem cell transplantation from unrelated donor.

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作者单位: Department of Immunogenetics, Institute of Hematology and Transfusion Medicine, Warsaw, Poland. Electronic address: jnowak@ihit.waw.pl. [1] Department of Immunogenetics, Institute of Hematology and Transfusion Medicine, Warsaw, Poland. [2] Department of Clinical Immunology, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland; Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wrocław, Poland. [3] Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wrocław, Poland. [4] Department of Hematopoietic Stem Cell Transplantation, Institute of Hematology and Transfusion Medicine, Warsaw, Poland. [5] Department of Hematology, Blood Malignancies and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland. [6] Department of Bone Marrow Transplantation and Oncohematology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch, Gliwice, Poland. [7] Department of Oncology Hematology and Paediatric Transplantology, Poznan University of Medical Sciences, Poznan, Poland. [8] Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland. [9] Department of Hematology and Transplantology, Gdansk Medical University Clinical Center, Gdansk, Poland. [10] Department of Hematology, Oncology and Internal Medicine, Warsaw Medical University, Warsaw, Poland. [11] Department of Hematology and Bone Marrow Transplantation, Silesian Medical University, Katowice, Poland. [12] Department of Pediatric Hematology Oncology and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland. [13] Department of Pediatric Hematology and Oncology, Collegium Medicum Nicolaus Copernicus University Hospital, Bydgoszcz, Poland. [14] Department of Paediatric Hematology, Oncology and Transplantology, Medical University, Lublin, Poland. [15] Department of Transplantation Children's University Hospital, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Cracow, Poland. [16] Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland. [17]
DOI 10.1016/j.humimm.2018.03.011
PMID 29605688
发布时间 2018-09-18
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Human immunology

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