Evaluation of anticonvulsant and analgesic activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides.

导出 LinkOut

翻译打印收藏纠错

作者： Anna,Rapacz ^[1] ; Monika,Głuch-Lutwin ^[2] ; Barbara,Mordyl ^[3] ; Barbara,Filipek ^[4] ; Michał,Abram ^[5] ; Krzysztof,Kamiński ^[6]

作者单位： Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: a.rapacz@uj.edu.pl. ^[1] Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: monika.gluch-lutwin@uj.edu.pl. ^[2] Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: barbara.mordyl@uj.edu.pl. ^[3] Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: mffilipe@cyf-kr.edu.pl. ^[4] Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: michal.abram@doctoral.uj.edu.pl. ^[5] Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address: k.kaminski@uj.edu.pl. ^[6]

关键词 Anticonvulsant activity Binding Hybrid compounds Pain models Pyrrolidine-2,5-dione Six-herz (6 Hz) test