The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A.

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作者： Claudia,Puri ^[1] ; Mariella,Vicinanza ^[1] ; Avraham,Ashkenazi ^[2] ; Matthew J,Gratian ^[3] ; Qifeng,Zhang ^[4] ; Carla F,Bento ^[2] ; Maurizio,Renna ^[1] ; Fiona M,Menzies ^[2] ; David C,Rubinsztein ^[5]

作者单位： Department of Medical Genetics, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. ^[1] Department of Medical Genetics, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. ^[2] Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. ^[3] Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK. ^[4] Department of Medical Genetics, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK; UK Dementia Research Institute, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic address: dcr1000@cam.ac.uk. ^[5]

关键词 RAB11A WIPI2 autophagy autophagy platform macroautophagy mitophagy recycling endosome transferrin receptor