Icariside II alleviates oxygen-glucose deprivation and reoxygenation-induced PC12 cell oxidative injury by activating Nrf2/SIRT3 signaling pathway.

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作者： Linying,Feng ^[1] ; Jianmei,Gao ^[2] ; Yuangui,Liu ^[1] ; Jingshan,Shi ^[1] ; Qihai,Gong ^[3]

作者单位： Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, PR China. ^[1] Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, PR China; Department of Clinical Pharmacotherapeutics, School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563000, PR China. ^[2] Department of Pharmacology, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, PR China. Electronic address: gqh@zmc.edu.cn. ^[3]

关键词 Apoptosis Icariside II Nrf2 Oxidative injury Oxygen-glucose deprivation Reoxygenation SIRT3