首页> American journal of respiratory and critical care medicine> Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.

Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.

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第一作者： Christine,Happle

第一单位： 1 Department of Pediatric Pneumology, Allergology and Neonatology.;2 Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Center for Lung Research (DZL).

作者： Christine,Happle ^[1] ; Nico,Lachmann ^[2] ; Mania,Ackermann ^[2] ; Anja,Mirenska ^[3] ; Gudrun,Göhring ^[4] ; Kathrin,Thomay ^[4] ; Adele,Mucci ^[5] ; Miriam,Hetzel ^[5] ; Torsten,Glomb ^[6] ; Takuji,Suzuki ^[7] ; Claudia,Chalk ^[7] ; Silke,Glage ^[8] ; Oliver,Dittrich-Breiholz ^[6] ; Bruce,Trapnell ^[7] ; Thomas,Moritz ^[5] ; Gesine,Hansen ^[1]

作者单位： 1 Department of Pediatric Pneumology, Allergology and Neonatology.;2 Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), Member of the German Center for Lung Research (DZL). ^[1] 3 Junior Research Group (JRG) Translational Hematology of Congenital Diseases, Regenerative Biology and Reconstructive Therapies (REBIRTH) Cluster of Excellence.;4 Institute of Experimental Hematology. ^[2] 1 Department of Pediatric Pneumology, Allergology and Neonatology. ^[3] 5 Department of Human Genetics. ^[4] 4 Institute of Experimental Hematology.;6 Research Group-Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence. ^[5] 7 Core Unit Transcriptomics, Institute for Physiological Chemistry, and. ^[6] 8 Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. ^[7] 9 Central Animal Facility, Hannover Medical School, Hannover, Germany; and. ^[8]

关键词 cell therapy induced pluripotent stem cell macrophages pulmonary alveolar proteinosis

医学主题词动物(Animals);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);巨噬细胞, 肺泡(Macrophages, Alveolar);小鼠(Mice);聚合酶链反应(Polymerase Chain Reaction);肺泡蛋白沉积症(Pulmonary Alveolar Proteinosis)

DOI 10.1164/rccm.201708-1562OC

PMID 29652170

发布时间 2019-11-08

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