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Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness.

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第一作者： Edit,Mikó

第一单位： Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032, Hungary; MTA-DE Lendület Laboratory of Cellular Metabolism, Debrecen 4032, Hungary.

作者： Edit,Mikó ^[1] ; András,Vida ^[1] ; Tünde,Kovács ^[2] ; Gyula,Ujlaki ^[2] ; György,Trencsényi ^[3] ; Judit,Márton ^[2] ; Zsanett,Sári ^[2] ; Patrik,Kovács ^[2] ; Anita,Boratkó ^[2] ; Zoltán,Hujber ^[4] ; Tamás,Csonka ^[5] ; Péter,Antal-Szalmás ^[6] ; Mitsuhiro,Watanabe ^[7] ; Imre,Gombos ^[8] ; Balazs,Csoka ^[9] ; Borbála,Kiss ^[10] ; László,Vígh ^[8] ; Judit,Szabó ^[11] ; Gábor,Méhes ^[5] ; Anna,Sebestyén ^[4] ; James J,Goedert ^[12] ; Péter,Bai ^[13]

作者单位： Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032, Hungary; MTA-DE Lendület Laboratory of Cellular Metabolism, Debrecen 4032, Hungary. ^[1] Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[2] Department of Medical Imaging, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[3] 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, 1085, Hungary. ^[4] Department of Pathology, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[5] Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[6] Department of Internal Medicine, School of Medicine, Keio University Endo, Fujisawa-shi, Kanagawa 252-0882, Japan. ^[7] Biological Research Center, 6701 Szeged, Hungary. ^[8] Deptartment of Anesthesiology, Columbia University Medical Center, New York, NY 10032, USA. ^[9] Department of Dermatology, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[10] Department of Microbiology, Faculty of Medicine, University of Debrecen, 4032, Hungary. ^[11] National Cancer Institute, National Institutes of Health, Bethesda, 20982, MD, USA. ^[12] Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032, Hungary; Department of Research Center for Molecular Medicine, Faculty of Medicine, University of Debrecen, 4032, Hungary; MTA-DE Lendület Laboratory of Cellular Metabolism, Debrecen 4032, Hungary. Electronic address: baip@med.unideb.hu. ^[13]

关键词 Breast cancer Endothelial-mesenchymal transition Lithocholic acid Microbiome OXPHOS TGR5