换一批
第一作者：
Samra,Turajlic
第一单位：
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Renal and Skin Units, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
作者：
Samra,Turajlic [1]
;
Hang,Xu [2]
;
Kevin,Litchfield [2]
;
Andrew,Rowan [2]
;
Stuart,Horswell [3]
;
Tim,Chambers [2]
;
Tim,O'Brien [4]
;
Jose I,Lopez [5]
;
Thomas B K,Watkins [2]
;
David,Nicol [6]
;
Mark,Stares [2]
;
Ben,Challacombe [4]
;
Steve,Hazell [7]
;
Ashish,Chandra [8]
;
Thomas J,Mitchell [9]
;
Lewis,Au [10]
;
Claudia,Eichler-Jonsson [2]
;
Faiz,Jabbar [2]
;
Aspasia,Soultati [11]
;
Simon,Chowdhury [11]
;
Sarah,Rudman [11]
;
Joanna,Lynch [10]
;
Archana,Fernando [4]
;
Gordon,Stamp [12]
;
Emma,Nye [12]
;
Aengus,Stewart [3]
;
Wei,Xing [13]
;
Jonathan C,Smith [13]
;
Mickael,Escudero [3]
;
Adam,Huffman [13]
;
Nik,Matthews [14]
;
Greg,Elgar [14]
;
Ben,Phillimore [14]
;
Marta,Costa [14]
;
Sharmin,Begum [14]
;
Sophia,Ward [15]
;
Max,Salm [3]
;
Stefan,Boeing [3]
;
Rosalie,Fisher [2]
;
Lavinia,Spain [10]
;
Carolina,Navas [2]
;
Eva,Grönroos [2]
;
Sebastijan,Hobor [2]
;
Sarkhara,Sharma [2]
;
Ismaeel,Aurangzeb [2]
;
Sharanpreet,Lall [11]
;
Alexander,Polson [8]
;
Mary,Varia [8]
;
Catherine,Horsfield [8]
;
Nicos,Fotiadis [16]
;
Lisa,Pickering [10]
;
Roland F,Schwarz [17]
;
Bruno,Silva [13]
;
Javier,Herrero [18]
;
Nick M,Luscombe [19]
;
Mariam,Jamal-Hanjani [20]
;
Rachel,Rosenthal [21]
;
Nicolai J,Birkbak [22]
;
Gareth A,Wilson [22]
;
Orsolya,Pipek [23]
;
Dezso,Ribli [23]
;
Marcin,Krzystanek [24]
;
Istvan,Csabai [23]
;
Zoltan,Szallasi [25]
;
Martin,Gore [10]
;
Nicholas,McGranahan [20]
;
Peter,Van Loo [26]
;
Peter,Campbell [27]
;
James,Larkin [28]
;
Charles,Swanton [29]
;
TRACERx Renal Consortium
作者单位：
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Renal and Skin Units, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
[1]
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK.
[2]
Department of Bioinformatics and Biostatistics, the Francis Crick Institute, London NW1 1AT, UK.
[3]
Urology Centre, Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK.
[4]
Department of Pathology, Cruces University Hospital, Biocruces Institute, University of the Basque Country, Barakaldo, Spain.
[5]
Department of Urology, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
[6]
Department of Pathology, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
[7]
Department of Pathology, Guy's and St. Thomas' NHS Foundation Trust, London SE1 7EH, UK.
[8]
Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK; Department of Surgery, Addenbrooke's Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
[9]
Renal and Skin Units, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
[10]
Department of Medical Oncology, Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK.
[11]
Experimental Histopathology Laboratory, the Francis Crick Institute, London NW1 1AT, UK.
[12]
Department of Scientific Computing, the Francis Crick Institute, London NW1 1AT, UK.
[13]
Advanced Sequencing Facility, the Francis Crick Institute, London NW1 1AT, UK.
[14]
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Advanced Sequencing Facility, the Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK.
[15]
Department of Radiology, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
[16]
Berlin Institute for Medical Systems Biology, Max Delbrueck Center for Molecular Medicine, Berlin, Germany.
[17]
Bill Lyons Informatics Centre, UCL Cancer Institute, University College London, London WC1E 6DD, UK.
[18]
Bioinformatics and Computational Biology Laboratory, the Francis Crick Institute, London NW1 1AT, UK.
[19]
Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK.
[20]
Bill Lyons Informatics Centre, UCL Cancer Institute, University College London, London WC1E 6DD, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK.
[21]
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK.
[22]
Department of Physics of Complex Systems, ELTE Eötvös Loránd University, Budapest, Hungary.
[23]
Department of Bio and Health Informatics, Technical University of Denmark, Kgs Lyngby 2800, Denmark.
[24]
Department of Bio and Health Informatics, Technical University of Denmark, Kgs Lyngby 2800, Denmark; Computational Health Informatics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
[25]
Cancer Genomics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Department of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
[26]
Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
[27]
Renal and Skin Units, the Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK. Electronic address: james.larkin@rmh.nhs.uk.
[28]
Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK; Department of Medical Oncology, University College London Hospitals, London NW1 2BU, UK. Electronic address: charles.swanton@crick.ac.uk.
[29]
医学主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);等位基因(Alleles);癌, 肾细胞(Carcinoma, Renal Cell);染色体(Chromosomes);疾病恶化(Disease Progression);进化, 分子(Evolution, Molecular);女(雌)性(Female);遗传异质性(Genetic Heterogeneity);遗传变异(Genetic Variation);人类(Humans);肾肿瘤(Kidney Neoplasms);纵向研究(Longitudinal Studies);男(雄)性(Male);中年人(Middle Aged);模型, 统计学(Models, Statistical);突变(Mutation);肿瘤转移(Neoplasm Metastasis);表型(Phenotype);种系发生(Phylogeny);预后(Prognosis);前瞻性研究(Prospective Studies);序列分析, DNA(Sequence Analysis, DNA)
DOI
10.1016/j.cell.2018.03.043
PMID
29656894
发布时间
2025-05-30
- 浏览12
Cell
Cell
595-610.e11页
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