换一批
换一批Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A.
第一作者：
Bharadwaja,Vadloori
第一单位：
Department of Animal Biology, School of Life Sciences, University of Hyderabad, Prof. C.R. Rao Road, Gachibowli, Hyderabad, 500046, India.
作者：
主题词
酶抑制剂(Enzyme Inhibitors);叶酸(Folic Acid);人类(Humans);杜氏利什曼原虫(Leishmania donovani);甲氨蝶呤(Methotrexate);分子动力学模拟(Molecular Dynamics Simulation);多酶复合物(Multienzyme Complexes);植物提取物(Plant Extracts);四氢叶酸脱氢酶(Tetrahydrofolate Dehydrogenase);胸苷酸合酶(Thymidylate Synthase);睡茄属(Withania);醉茄内酯类(Withanolides)
DOI
10.1186/s13104-018-3354-1
PMID
29661206
发布时间
2018-11-14
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