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IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma.

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第一作者： Sha,Zhu

第一单位： Department of Molecular, Cell and Cancer Biology.

作者： Sha,Zhu ^[1] ; B Marie,Ward ^[2] ; Jun,Yu ^[1] ; Asia N,Matthew-Onabanjo ^[1] ; Jenny,Janusis ^[1] ; Chung-Cheng,Hsieh ^[1] ; Keith,Tomaszewicz ^[3] ; Lloyd,Hutchinson ^[3] ; Lihua Julie,Zhu ^[4] ; Dina,Kandil ^[3] ; Leslie M,Shaw ^[1]

作者单位： Department of Molecular, Cell and Cancer Biology. ^[1] Department of Surgery. ^[2] Department of Pathology. ^[3] Department of Molecular, Cell and Cancer Biology.;Department of Molecular Medicine, and.;Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA. ^[4]

关键词 Breast cancer Insulin signaling Oncology

医学主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);乳腺肿瘤(Breast Neoplasms);癌, 小叶状(Carcinoma, Lobular);女(雌)性(Female);人类(Humans);胰岛素受体底物蛋白质类(Insulin Receptor Substrate Proteins);淋巴结(Lymph Nodes);中年人(Middle Aged);突变, 误义(Mutation, Missense);肿瘤侵润(Neoplasm Invasiveness);肿瘤分期(Neoplasm Staging);受体, IGF1型(Receptor, IGF Type 1);受体, 生长调节素(Receptors, Somatomedin)

DOI 10.1172/jci.insight.97398

PMID 29669935

发布时间 2022-12-07

基金项目

F31 CA206378/CA/NCI NIH HHS/United States R01 CA142782/CA/NCI NIH HHS/United States

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