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作者：
Susanne,Müller [1]
;
Suzanne,Ackloo [2]
;
Cheryl H,Arrowsmith [3]
;
Marcus,Bauser [4]
;
Jeremy L,Baryza [5]
;
Julian,Blagg [6]
;
Jark,Böttcher [7]
;
Chas,Bountra [8]
;
Peter J,Brown [2]
;
Mark E,Bunnage [5]
;
Adrian J,Carter [9]
;
David,Damerell [8]
;
Volker,Dötsch [10]
;
David H,Drewry [11]
;
Aled M,Edwards [12]
;
James,Edwards [2]
;
Jon M,Elkins [13]
;
Christian,Fischer [8]
;
Stephen V,Frye [14]
;
Andreas,Gollner [15]
;
Charles E,Grimshaw [16]
;
Adriaan,IJzerman [17]
;
Thomas,Hanke [18]
;
Ingo V,Hartung [1]
;
Steve,Hitchcock [4]
;
Trevor,Howe [19]
;
Terry V,Hughes [20]
;
Stefan,Laufer [20]
;
Volkhart Mj,Li [21]
;
Spiros,Liras [22]
;
Brian D,Marsden [23]
;
Hisanori,Matsui [8]
;
John,Mathias [24]
;
Ronan C,O'Hagan [25]
;
Dafydd R,Owen [23]
;
Vineet,Pande [14]
;
Daniel,Rauh [23]
;
Saul H,Rosenberg [26]
;
Bryan L,Roth [27]
;
Natalie S,Schneider [28]
;
Cora,Scholten [29]
;
Kumar,Singh Saikatendu [1]
;
Anton,Simeonov [4]
;
Masayuki,Takizawa [19]
;
Chris,Tse [30]
;
Paul R,Thompson [31]
;
Daniel K,Treiber [28]
;
Amélia Yi,Viana [32]
;
Carrow I,Wells [33]
;
Timothy M,Willson [9]
;
William J,Zuercher [12]
;
Stefan,Knapp [12]
;
Anke,Mueller-Fahrnow [12]
作者单位：
Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
[1]
Structural Genomics Consortium, University of Toronto, Toronto, Canada.
[2]
Department of Medical Biophysics, University of Toronto, Toronto, Canada.
[3]
Drug Discovery Pharmaceuticals, Bayer AG, Berlin, Germany.
[4]
Vertex Pharmaceuticals, Boston, United States.
[5]
Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, United Kingdom.
[6]
Discovery Research, Boehringer Ingelheim, Vienna, Austria.
[7]
Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
[8]
Discovery Research, Boehringer Ingelheim, Ingelheim am Rhein, Germany.
[9]
Institute of Biophysical Chemistry, Goethe-University, Frankfurt am Main, Germany.
[10]
Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt am Main, Germany.
[11]
Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, United States.
[12]
Janssen Pharmaceutical Research and Development LLC, Spring House, United States.
[13]
Merck & Co., Inc., Boston, United States.
[14]
Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, United States.
[15]
Discovery Research, Boehringer Ingelheim, Biberach an der Riss, Germany.
[16]
Ched Grimshaw Consulting, LLC, Poway, United States.
[17]
Division of Medicinal Chemistry, Leiden University, Leiden, Netherlands.
[18]
Takeda California Inc., San Diego, United States.
[19]
J&J Innovation Centre, London, United Kingdom.
[20]
Department of Pharmaceutical Chemistry, Eberhard Karls Universität Tübingen, Tübingen, Germany.
[21]
Drug Discovery Pharmaceuticals, Bayer AG, Wuppertal, Germany.
[22]
Worldwide Medicinal Chemistry, Pfizer, Cambridge, United States.
[23]
Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.
[24]
Takeda Pharmaceutical Company Ltd, Fujisawa, Japan.
[25]
Discovery Sciences, Janssen-Pharmaceutical Companies of Johnson & Johnson, Beerse, Belgium.
[26]
Fakultät für Chemie und Chemische Biologie, Technische Universität Dortmund, Dortmund, Germany.
[27]
AbbVie, North Chicago, United States.
[28]
The National Institute of Mental Health Psychoactive Active Drug Screening Program, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, United States.
[29]
National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, United States.
[30]
Takeda Pharmaceutical Company Ltd., Fujisawa, Japan.
[31]
Department of Biochemistry and Pharmacology, University of Massachusetts Medical School, Worcester, United States.
[32]
Eurofins DiscoverX, Sane Diego, United States.
[33]
DOI
10.7554/eLife.34311
PMID
29676732
发布时间
2024-02-13
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