首页> BMJ open> Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial.

Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial.

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第一作者： Kenneth T,Shelton

第一单位： Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

作者： Kenneth T,Shelton ^[1] ; Jason,Qu ^[1] ; Federico,Bilotta ^[2] ; Emery N,Brown ^[3] ; Gaston,Cudemus ^[1] ; David A,D'Alessandro ^[4] ; Hao,Deng ^[1] ; Alan,DiBiasio ^[5] ; Jacob A,Gitlin ^[1] ; Eunice Y,Hahm ^[1] ; Lauren E,Hobbs ^[1] ; Timothy T,Houle ^[1] ; Reine,Ibala ^[1] ; Marco L,Loggia ^[6] ; Kara J,Pavone ^[1] ; Shahzad,Shaefi ^[7] ; George,Tolis ^[4] ; M Brandon,Westover ^[8] ; Oluwaseun,Akeju ^[1]

作者单位： Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[1] Department of Anaesthesia and Critical Care Medicine, Sapienza University of Rome, Rome, Italy. ^[2] Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.;Institute for Medical Engineering and Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. ^[3] Department of Surgery, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[4] Department of Pharmacy, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[5] Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[6] Department of Anesthesia and Critical Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. ^[7] Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA. ^[8]

关键词 biomimetic sleep cardiac surgery delirium dexmedetomidine patient reported outcomes