首页> Journal of hematology & oncology> miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy.

miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy.

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第一作者： Qian,Huang

第一单位： Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.

作者： Qian,Huang ^[1] ; Jiajia,Xia ^[1] ; Lei,Wang ^[2] ; Xu,Wang ^[1] ; Xiaodong,Ma ^[2] ; Qipan,Deng ^[1] ; Yong,Lu ^[1] ; Munish,Kumar ^[3] ; Zhiyuan,Zhou ^[4] ; Ling,Li ^[5] ; Zhaoyang,Zeng ^[6] ; Ken H,Young ^[7] ; Qing,Yi ^[1] ; Mingzhi,Zhang ^[5] ; Yong,Li ^[8]

作者单位： Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. ^[1] Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.;Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China. ^[2] Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.;Raman Fellow (UGC), Department of Biochemistry, University of Allahabad, Allahabad, India. ^[3] Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.;Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Lymphoma Diagnosis and Treatment Center of Henan Province, Zhengzhou, 450000, Henan Province, China. ^[4] Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Lymphoma Diagnosis and Treatment Center of Henan Province, Zhengzhou, 450000, Henan Province, China. ^[5] Cancer Research Institute, Central South University, Changsha, 410078, China. ^[6] Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA. ^[7] Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. liy2@ccf.org. ^[8]

关键词 Chimeric antigen receptor (CAR)Colon cancer Indoleamine 2,3-dioxygenase 1 (IDO1)T cells Tumor microenvironment miR-153