首页> Proceedings of the National Academy of Sciences of the United States of America> Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (<i>CFH</i>) gene family.

Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (<i>CFH</i>) gene family.

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第一作者： Stuart,Cantsilieris

第一单位： Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195.

作者： Stuart,Cantsilieris ^[1] ; Bradley J,Nelson ^[1] ; John,Huddleston ^[2] ; Carl,Baker ^[1] ; Lana,Harshman ^[1] ; Kelsi,Penewit ^[1] ; Katherine M,Munson ^[1] ; Melanie,Sorensen ^[1] ; AnneMarie E,Welch ^[1] ; Vy,Dang ^[1] ; Felix,Grassmann ^[3] ; Andrea J,Richardson ^[4] ; Robyn H,Guymer ^[4] ; Tina A,Graves-Lindsay ^[5] ; Richard K,Wilson ^[6] ; Bernhard H F,Weber ^[3] ; Paul N,Baird ^[4] ; Rando,Allikmets ^[7] ; Evan E,Eichler ^[8]

作者单位： Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195. ^[1] Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195.;Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195. ^[2] Institute of Human Genetics, University of Regensburg, 93053 Regensburg, Germany. ^[3] Centre for Eye Research Australia, Department of Surgery (Ophthalmology), University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia. ^[4] McDonnell Genome Institute at Washington University, St. Louis, MO 63108. ^[5] Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43205.;Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH 93053. ^[6] Department of Ophthalmology, Columbia University, New York, NY 10027.;Department of Pathology and Cell Biology, Columbia University, New York, NY 10027. ^[7] Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195; eee@gs.washington.edu.;Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195. ^[8]

关键词 AMD CFH gene family age-related macular degeneration natural selection structural variation