Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism.
第一作者:
Murali,Ganesan
第一单位:
Research Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, Nebraska.;Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
作者:
关键词
4-MP, 4-methylpirazoleADH, alcohol dehydrogenaseAGS, acetaldehyde-generating systemAMI-1, protein arginine N-methyltransferase inhibitorAch, acetaldehydeAlcoholBHMT, betaine-homocysteine-S-methyltransferaseCYP2E1, cytochrome P450 2E1HCVHCV, hepatitis C virusIFN, interferonISG, interferon-stimulated geneJAK-STAT, Janus kinase–STAT, signal transducer and activator of transcriptionJMJD6JMJD6, jumonji domain-containing 6 proteinOA, okadaic acidOAS-1, 2’-5’-oligoadenylate synthetase-1OASL, 2’-5’-oligoadenylate synthetase-like proteinPCR, polymerase chain reactionPP2A, protein phosphatase 2APRMT1, protein methyl transferase 1RT, reverse-transcriptionSAM, S-adenosylmethionineSTAT1TK-NOG, thymidine kinase transgene-NOD/Shi-scid/IL-2Rγnull micecDNA, complementary DNAmRNA, messenger RNAsiRNA, short interfering RNA
DOI
10.1016/j.jcmgh.2017.10.004
PMID
29693039
发布时间
2022-03-18
- 浏览19
Cellular and molecular gastroenterology and hepatology
2018年5卷2期
101-112页
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