A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.

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第一作者： Shijie C,Zheng

第一单位： CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, 320 Yue Yang Road, Shanghai 200031, PR China.

作者： Shijie C,Zheng ^[1] ; Amy P,Webster ^[2] ; Danyue,Dong ^[3] ; Andy,Feber ^[1] ; David G,Graham ^[2] ; Roisin,Sullivan ^[4] ; Sarah,Jevons ^[4] ; Laurence B,Lovat ^[4] ; Stephan,Beck ^[4] ; Martin,Widschwendter ^[4] ; Andrew E,Teschendorff ^[3]

作者单位： CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, 320 Yue Yang Road, Shanghai 200031, PR China. ^[1] University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, PR China. ^[2] UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6BT, UK. ^[3] Division of Surgery & Interventional Science, UCL, London WC1E 6BT, UK. ^[4] Department of Women's Cancer, University College London, 74 Huntley Street, London WC1E 6AU, UK. ^[5]

关键词 DNA methylation EWAS buccal cell-type heterogeneity cervix immune cell saliva surrogate tissue