Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture.

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第一作者： Yossef,Alnasser

第一单位： Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. yossefalnasser@gmail.com.

作者： Yossef,Alnasser ^[1] ; Siva P,Kambhampati ^[2] ; Elizabeth,Nance ^[3] ; Labchan,Rajbhandari ^[4] ; Shiva,Shrestha ^[5] ; Arun,Venkatesan ^[6] ; Rangaramanujam M,Kannan ^[7] ; Sujatha,Kannan ^[8]

作者单位： Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. yossefalnasser@gmail.com. ^[1] Center for Nanomedicine, Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins, University School of Medicine, Baltimore, MD 21205, USA. skpramodh@gmail.com. ^[2] Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. eanance@gmail.com. ^[3] Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. labchanr@gmail.com. ^[4] Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. shivashrestha09@gmail.com. ^[5] Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. avenkat2@jhmi.edu. ^[6] Center for Nanomedicine, Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins, University School of Medicine, Baltimore, MD 21205, USA. krangar1@jhmi.edu. ^[7] Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. skannan3@jhmi.edu. ^[8] Center for Nanomedicine, Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins, University School of Medicine, Baltimore, MD 21205, USA. skannan3@jhmi.edu. ^[9]

关键词 PAMAM hydroxyl dendrimers activated microglia enhanced cellular uptake intracellular trafficking mixed primary glial cultures neuroinflammation