Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.

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作者： Riccardo E,Marioni ^[1] ; Matthew,Suderman ^[2] ; Brian H,Chen ^[3] ; Steve,Horvath ^[4] ; Stefania,Bandinelli ^[5] ; Tiffany,Morris ^[6] ; Stephan,Beck ^[7] ; Luigi,Ferrucci ^[8] ; Nancy L,Pedersen ^[8] ; Caroline L,Relton ^[4] ; Ian J,Deary ^[9] ; Sara,Hägg ^[3]

作者单位： Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK. ^[1] Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, UK. ^[2] Medical Research Council Integrative Epidemiology Unit, University of Bristol, UK. ^[3] The National Institute on Aging, NIH, Baltimore, Maryland. ^[4] Human Genetics, David Geffen School of Medicine, University of California Los Angeles. ^[5] Department of Biostatistics, School of Public Health, University of California Los Angeles. ^[6] Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy. ^[7] UCL Cancer Institute, University College London, UK. ^[8] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. ^[9] Department of Psychology, University of Edinburgh, UK. ^[10]

主题词衰老(Aging);DNA(DNA);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);人类(Humans);长寿(Longevity)

DOI 10.1093/gerona/gly060

PMID 29718110

发布时间 2024-04-06

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