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Acquired thrombotic thrombocytopenic purpura with isolated CFHR3/1 deletion-rapid remission following complement blockade.

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第一作者： Martin,Bitzan

第一单位： Division of Nephrology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Room B RC.6651, Montreal, Québec, H4A 3J1, Canada. martin.bitzan@mcgill.ca.

作者： Martin,Bitzan ^[1] ; Rawan M,Hammad ^[2] ; Arnaud,Bonnefoy ^[3] ; Watfa Shahwan,Al Dhaheri ^[4] ; Catherine,Vézina ^[5] ; Georges-Étienne,Rivard ^[3]

作者单位： Division of Nephrology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Room B RC.6651, Montreal, Québec, H4A 3J1, Canada. martin.bitzan@mcgill.ca. ^[1] Division of Nephrology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Room B RC.6651, Montreal, Québec, H4A 3J1, Canada. ^[2] Service d'hématologie-oncologie, CHU Sainte-Justine and Université de Montréal, Montréal, Canada. ^[3] Division of Nephrology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Room B RC.6651, Montreal, Québec, H4A 3J1, Canada.;Department of Pediatric, Tawam Hospital, Al Ain, United Arab Emirates. ^[4] Division of Hematology/Oncology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Canada. ^[5]

关键词 ADAMTS13 Atypical hemolytic uremic syndrome Complement factor H-related protein Eculizumab Thrombotic microangiopathy Ultra-large von Willebrand factor multimers