The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis.-论文-万方医学网

作者： Ivy M,Dambuza ^[1] ; Thomas,Drake ^[1] ; Ambre,Chapuis ^[1] ; Xin,Zhou ^[2] ; Joao,Correia ^[1] ; Leanne,Taylor-Smith ^[2] ; Nathalie,LeGrave ^[2] ; Tim,Rasmussen ^[3] ; Matthew C,Fisher ^[4] ; Tihana,Bicanic ^[3] ; Thomas S,Harrison ^[5] ; Marcel,Jaspars ^[6] ; Robin C,May ^[7] ; Gordon D,Brown ^[7] ; Raif,Yuecel ^[3] ; Donna M,MacCallum ^[2] ; Elizabeth R,Ballou ^[1]

作者单位： Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom. ^[1] Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, United Kingdom. ^[2] Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen, United Kingdom. ^[3] Francis Crick Institute, London, United Kingdom. ^[4] Institut für Biochemie, Universität Würzburg, Wurzburg, Germany. ^[5] Dpt. Infectious Disease Epidemiology, Imperial College London, London, United Kingdom. ^[6] Institute of Infection and Immunity, St George's University of London, London, United Kingdom. ^[7]

主题词动物(Animals);隐球菌病(Cryptococcosis);新型隐球菌(Cryptococcus neoformans);环AMP(Cyclic AMP);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);真菌蛋白质类(Fungal Proteins);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);菌丝(Hyphae);肺(Lung);肺疾病, 真菌性(Lung Diseases, Fungal);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);显微镜检查, 电子, 透射(Microscopy, Electron, Transmission);模型, 生物学(Models, Biological);形态发生(Morphogenesis);多倍性(Polyploidy);转录因子(Transcription Factors);毒力(Virulence)

DOI 10.1371/journal.ppat.1006978

PMID 29775474

发布时间 2023-11-15

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The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis.

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The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis.

PLoS pathogens

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PLoS pathogens

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