Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry.

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作者： Riya,Shrestha ^[1] ; Jung Jae,Jo ^[1] ; DooHyun,Lee ^[1] ; Taeho,Lee ^[1] ; Sangkyu,Lee ^[1]

作者单位： a BK21 Plus KNU Multi-Omics-Based Creative Drug Research Team, College of Pharmacy, Research Institute of Pharmaceutical Sciences , Kyungpook National University , Daegu , Republic of Korea. ^[1]

关键词 LC-MS/MS Leelamine cytochrome P450 human liver microsomes metabolite

主题词动物(Animals);色谱法, 液相(Chromatography, Liquid);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);二萜类(Diterpenes);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交ICR(Mice, Inbred ICR);微粒体, 肝(Microsomes, Liver);松属(Pinus);植物皮(Plant Bark);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1080/00498254.2018.1480816

PMID 29790809

发布时间 2019-04-24

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Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry.

Xenobiotica; the fate of foreign compounds in biological systems

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Xenobiotica; the fate of foreign compounds in biological systems

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Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry.

Xenobiotica; the fate of foreign compounds in biological systems

相似文献

Xenobiotica; the fate of foreign compounds in biological systems

相关期刊

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