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Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer.

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第一作者: Sonja,Neumeyer
第一单位: Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
作者单位: Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98124, USA. [2] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [3] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892-9776, USA. [4] Centre Hospitalier Universitaire (CHU), Nantes Service de Génétique Médicale, 44093, Nantes, France. [5] Colorectal Oncogenomics Group, Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC, 3010, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia. [6] Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland, 94612, CA, USA. [7] Epidemiology Research Program, American Cancer Society, Atlanta, GA, 30329-4251, USA. [8] Center for Public Health Genomics, University of Virginia, Charlottesville, VA, 22908, USA. [9] Clinical and Translational Epidemiology Unit and Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, 02115, USA.;Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.;Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA. [10] Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1 X 5, Canada. [11] Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.;Department of Epidemiology, Harvard School of Public Health, Boston, MA, 02115, USA.;Department of Nutrition, Harvard School of Public Health, Boston, MA, 02115, USA.;Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA. [12] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia.;Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, VIC, 3010, Australia. [13] Department of Medicine, Division of Gastroenterology, University of Washington School of Medicine, Seattle, WA, 98195, USA.;Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. [14] Medical Department 1, University Hospital Dresden, TU Dresden, 01307, Dresden, Germany. [15] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia. [16] Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.;Department of Epidemiology, Harvard School of Public Health, Boston, MA, 02115, USA. [17] Institute of Environmental Medicine, Karolinska Institutet Solna, SE-171 77, Stockholm, Sweden. [18] Epidemiology Program, University of Hawaii Cancer Center, Honolulu, 96822, HI, USA. [19] Department of Clinical Genetics, Karolinska University Hospital Solna, SE-171 77, Stockholm, Sweden.;Department of Molecular Medicine and Surgery, Karolinska Institutet Solna, SE-171 77, Stockholm, Sweden. [20] Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), 08028, Barcelona, Spain.;CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain and University of Barcelona, Barcelona, 08007, Spain. [21] Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada. [22] Department of Family Medicine and Community Health, Case Western Reserve University, Cleveland, OH, 44106, USA. [23] Department of Medicine, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. [24] Centre for Cancer Genetic Epidemiology, Department of Public Health & Primary Care, University of Cambridge, Cambridge, CB2 8AR, UK. [25] Department of Public Health Sciences, University of California, Davis, CA, 95817, USA. [26] Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.;Clalit Health Services National Israeli Cancer Control Center, Haifa, 34361, Israel.;Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, 34361, Israel. [27] Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24118, Kiel, Germany. [28] Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 15213, USA. [29] Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, 84108, USA. [30] Clinical and Translational Epidemiology Unit and Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, 02115, USA.;Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, USA.;Department of Nutrition, Harvard School of Public Health, Boston, MA, 02115, USA. [31] Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, Salt Lake City, UT, 84112, USA. [32] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia.;Genetic Medicine and Familial Cancer Centre, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia. [33] Institute of Environmental Medicine, Karolinska Institutet Solna, SE-171 77, Stockholm, Sweden.;Department of Surgical Sciences, Uppsala University, Uppsala, SE-171 77, Sweden. [34] Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, A1C 5S7, Canada. [35] Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 90033, USA. [36] Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, 90033, USA. [37] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.;Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120, Heidelberg, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [38] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. j.chang-claude@dkfz-heidelberg.de.;Genetic Tumour Epidemiology Group, University Medical Center Hamburg-Eppendorf, University Cancer Center Hamburg, 20246, Hamburg, Germany. j.chang-claude@dkfz-heidelberg.de. [39]
DOI 10.1038/s41416-018-0108-8
PMID 29795306
发布时间 2025-07-03
基金项目
U01 HG004438/HG/NHGRI NIH HHS/United States U01 HG004446/HG/NHGRI NIH HHS/United States P01 CA087969/CA/NCI NIH HHS/United States HHSN268201100046C/HL/NHLBI NIH HHS/United States P30 CA076292/CA/NCI NIH HHS/United States R01 CA054281/CA/NCI NIH HHS/United States U24 CA074799/CA/NCI NIH HHS/United States HHSN268201100004C/WH/WHI NIH HHS/United States U19 CA148107/CA/NCI NIH HHS/United States R01 CA059045/CA/NCI NIH HHS/United States HHSN268201100001I/HL/NHLBI NIH HHS/United States R01 CA197350/CA/NCI NIH HHS/United States R01 CA076366/CA/NCI NIH HHS/United States R35 CA197735/CA/NCI NIH HHS/United States U01 CA074799/CA/NCI NIH HHS/United States HHSN268201600002C/HL/NHLBI NIH HHS/United States P30 CA015704/CA/NCI NIH HHS/United States HHSN268201600018C/HL/NHLBI NIH HHS/United States HHSN268201100004I/HL/NHLBI NIH HHS/United States Z01 CP010200/ImNIH/Intramural NIH HHS/United States K01 DK110267/DK/NIDDK NIH HHS/United States K05 CA154337/CA/NCI NIH HHS/United States U24 CA074783/CA/NCI NIH HHS/United States R01 CA151993/CA/NCI NIH HHS/United States R01 CA189184/CA/NCI NIH HHS/United States R01 CA048998/CA/NCI NIH HHS/United States U01 CA137088/CA/NCI NIH HHS/United States HHSN268201100003C/WH/WHI NIH HHS/United States U24 CA074794/CA/NCI NIH HHS/United States U24 CA074806/CA/NCI NIH HHS/United States U01 CA206110/CA/NCI NIH HHS/United States R01 CA137178/CA/NCI NIH HHS/United States U24 CA097735/CA/NCI NIH HHS/United States U01 CA074794/CA/NCI NIH HHS/United States P30 CA008748/CA/NCI NIH HHS/United States U01 CA167551/CA/NCI NIH HHS/United States R01 CA081488/CA/NCI NIH HHS/United States P30 CA014089/CA/NCI NIH HHS/United States R01 CA189532/CA/NCI NIH HHS/United States R01 CA143237/CA/NCI NIH HHS/United States HHSN268201600003C/HL/NHLBI NIH HHS/United States HHSN271201100004C/AG/NIA NIH HHS/United States R01 CA063464/CA/NCI NIH HHS/United States P01 CA033619/CA/NCI NIH HHS/United States UM1 CA186107/CA/NCI NIH HHS/United States HHSN268201100002C/WH/WHI NIH HHS/United States R01 CA207371/CA/NCI NIH HHS/United States HHSN268201600004C/HL/NHLBI NIH HHS/United States R01 CA060987/CA/NCI NIH HHS/United States U01 CA097735/CA/NCI NIH HHS/United States HHSN268201600001C/HL/NHLBI NIH HHS/United States UM1 CA167551/CA/NCI NIH HHS/United States U01 CA122839/CA/NCI NIH HHS/United States S10 OD020069/OD/NIH HHS/United States HHSN268201100003I/HL/NHLBI NIH HHS/United States HHSN268201100002I/HL/NHLBI NIH HHS/United States U01 CA074783/CA/NCI NIH HHS/United States U01 CA074806/CA/NCI NIH HHS/United States U24 CA074800/CA/NCI NIH HHS/United States P50 CA127003/CA/NCI NIH HHS/United States K07 CA190673/CA/NCI NIH HHS/United States U01 CA152756/CA/NCI NIH HHS/United States R37 CA054281/CA/NCI NIH HHS/United States U01 CA074800/CA/NCI NIH HHS/United States HHSN268201100001C/WH/WHI NIH HHS/United States
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