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首页> The pharmacogenomics journal> Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity.

Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity.

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作者： Ruowang,Li ^[1] ; Dokyoon,Kim ^[2] ; Heather E,Wheeler ^[3] ; Scott M,Dudek ^[4] ; M Eileen,Dolan ^[2] ; Marylyn D,Ritchie ^[5]

作者单位： Bioinformatics and Genomics program, Pennsylvania State University, University Park, Pennsylvania, USA. ^[1] Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. ^[2] Biomedical and Translational Informatics, Geisinger, Danville, Pennsylvania, USA. ^[3] Departments of Biology and Computer Science, Loyola University Chicago, Chicago, Illinois, USA. ^[4] Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. ^[5] Department of Medicine, University of Chicago, Chicago, Illinois, USA. ^[6] Bioinformatics and Genomics program, Pennsylvania State University, University Park, Pennsylvania, USA. marylyn@pennmedicine.upenn.edu. ^[7] Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. marylyn@pennmedicine.upenn.edu. ^[8] Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. marylyn@pennmedicine.upenn.edu. ^[9]

主题词卡铂(Carboplatin);细胞系(Cell Line);顺铂(Cisplatin);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);遗传变异(Genetic Variation);基因组, 人(Genome, Human);全基因组关联研究(Genome-Wide Association Study);人类(Humans);分子序列注释(Molecular Sequence Annotation);肿瘤(Neoplasms);紫杉酚(Paclitaxel);遗传药理学(Pharmacogenetics);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1038/s41397-018-0024-6

PMID 29795408

发布时间 2022-12-07

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The pharmacogenomics journal

The pharmacogenomics journal

2019年19卷2期

178-190页

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