Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.

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作者： Kshipra,Singh ^[1] ; Lori A,Coburn ^[2] ; Mohammad,Asim ^[1] ; Daniel P,Barry ^[2] ; Margaret M,Allaman ^[3] ; Chanjuan,Shi ^[1] ; M Kay,Washington ^[1] ; Paula B,Luis ^[1] ; Claus,Schneider ^[4] ; Alberto G,Delgado ^[5] ; M Blanca,Piazuelo ^[4] ; John L,Cleveland ^[5] ; Alain P,Gobert ^[6] ; Keith T,Wilson ^[2]

作者单位： Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. ^[1] Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee. ^[2] Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee. ^[3] Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee. ^[4] Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee. ^[5] Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee. ^[6] Department of Tumor Biology, Moffitt Cancer Center and Research Institute, Tampa, Florida. ^[7] Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. keith.wilson@vanderbilt.edu. ^[8]