ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study.

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第一作者： Mark C,Genovese

第一单位： Stanford University Medical Center, Palo Alto, California.

作者： Mark C,Genovese ^[1] ; Michael E,Weinblatt ^[2] ; Jacob A,Aelion ^[3] ; Heikki T,Mansikka ^[4] ; Paul M,Peloso ^[4] ; Kun,Chen ^[4] ; Yihan,Li ^[4] ; Ahmed A,Othman ^[4] ; Amit,Khatri ^[4] ; Nasser S,Khan ^[4] ; Robert J,Padley ^[4]

作者单位： Stanford University Medical Center, Palo Alto, California. ^[1] Brigham and Women's Hospital, Boston, Massachusetts. ^[2] University of Tennessee Heath Science Center, Memphis, Tennessee. ^[3] AbbVie Incorporated, North Chicago, Illinois. ^[4]

主题词成年人(Adult);老年人(Aged);抗风湿药(Antirheumatic Agents);关节炎, 类风湿(Arthritis, Rheumatoid);双盲法(Double-Blind Method);女(雌)性(Female);人类(Humans);免疫球蛋白类(Immunoglobulins);白细胞介素17(Interleukin-17);男(雄)性(Male);甲氨蝶呤(Methotrexate);中年人(Middle Aged);治疗结果(Treatment Outcome);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)

DOI 10.1002/art.40580

PMID 29855172

发布时间 2020-02-25

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Arthritis & rheumatology (Hoboken, N.J.)

2018年70卷11期

1710-1720页

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ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

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ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

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