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首页> Vaccine> In ovo administration of Toll-like receptor ligands encapsulated in PLGA nanoparticles impede tumor development in chickens infected with Marek's disease virus.

In ovo administration of Toll-like receptor ligands encapsulated in PLGA nanoparticles impede tumor development in chickens infected with Marek's disease virus.

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作者： Jegarubee,Bavananthasivam ^[1] ; Tamiru N,Alkie ^[1] ; Jake,Astill ^[1] ; Mohamed Faizal,Abdul-Careem ^[2] ; Sarah K,Wootton ^[1] ; Shahriar,Behboudi ^[3] ; Alexander,Yitbarek ^[1] ; Shayan,Sharif ^[4]

作者单位： Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. ^[1] Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada. ^[2] The Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, United Kingdom; Department of Pathology and Infectious Disease, School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom. ^[3] Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. Electronic address: shayan@uoguelph.ca. ^[4]

关键词 Chicken embryos Cytokine genes In ovo administration Marek’s disease virus PLGA encapsulation TLR ligands

主题词佐剂, 免疫(Adjuvants, Immunologic);动物(Animals);鸡(Chickens);细胞因子类(Cytokines);免疫, 先天(Immunity, Innate);发病率(Incidence);乳酸(Lactic Acid);脂多糖类(Lipopolysaccharides);Marek病(Marek Disease);纳米粒子(Nanoparticles);寡脱氧核糖核苷酸类(Oligodeoxyribonucleotides);聚乙醇酸(Polyglycolic Acid);Toll样受体(Toll-Like Receptors);治疗结果(Treatment Outcome)

DOI 10.1016/j.vaccine.2018.05.091

PMID 29859800

发布时间 2018-12-02

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Vaccine

Vaccine

2018年36卷28期

4070-4076页

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