换一批
换一批Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
作者：
Kai,Xu [1]
;
Priyamvada,Acharya [1]
;
Rui,Kong [2]
;
Cheng,Cheng [1]
;
Gwo-Yu,Chuang [1]
;
Kevin,Liu [1]
;
Mark K,Louder [1]
;
Sijy,O'Dell [1]
;
Reda,Rawi [1]
;
Mallika,Sastry [1]
;
Chen-Hsiang,Shen [1]
;
Baoshan,Zhang [1]
;
Tongqing,Zhou [1]
;
Mangaiarkarasi,Asokan [1]
;
Robert T,Bailer [1]
;
Michael,Chambers [1]
;
Xuejun,Chen [1]
;
Chang W,Choi [1]
;
Venkata P,Dandey [1]
;
Nicole A,Doria-Rose [2]
;
Aliaksandr,Druz [1]
;
Edward T,Eng [1]
;
S Katie,Farney [2]
;
Kathryn E,Foulds [1]
;
Hui,Geng [1]
;
Ivelin S,Georgiev [1]
;
Jason,Gorman [3]
;
Kurt R,Hill [1]
;
Alexander J,Jafari [1]
;
Young D,Kwon [1]
;
Yen-Ting,Lai [1]
;
Thomas,Lemmin [1]
;
Krisha,McKee [4]
;
Tiffany Y,Ohr [1]
;
Li,Ou [1]
;
Dongjun,Peng [1]
;
Ariana P,Rowshan [1]
;
Zizhang,Sheng [1]
;
John-Paul,Todd [5]
;
Yaroslav,Tsybovsky [6]
;
Elise G,Viox [1]
;
Yiran,Wang [7]
;
Hui,Wei [1]
;
Yongping,Yang [1]
;
Amy F,Zhou [2]
;
Rui,Chen [1]
;
Lu,Yang [1]
;
Diana G,Scorpio [8]
;
Adrian B,McDermott [8]
;
Lawrence,Shapiro [1]
;
Bridget,Carragher [1]
;
Clinton S,Potter [1]
;
John R,Mascola [5]
;
Peter D,Kwong [6]
作者单位：
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
[1]
National Resource for Automated Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.
[2]
Vanderbilt Vaccine Center, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, and Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, USA.
[3]
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
[4]
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
[5]
Department of Systems Biology, Columbia University, New York, NY, USA.
[6]
Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
[7]
GenScript USA, Piscataway, NJ, USA.
[8]
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. jmascola@nih.gov.
[9]
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. pdkwong@nih.gov.
[10]
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. pdkwong@nih.gov.
[11]
主题词
艾滋病疫苗(AIDS Vaccines);氨基酸序列(Amino Acid Sequence);动物(Animals);抗体, 中和(Antibodies, Neutralizing);表位(Epitopes);女(雌)性(Female);豚鼠(Guinea Pigs);HIV抗体(HIV Antibodies);HIV-1(HIV-1);免疫法(Immunization);猕猴(Macaca mulatta);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 分子(Models, Molecular);中和试验(Neutralization Tests);肽类(Peptides);重组融合蛋白质类(Recombinant Fusion Proteins);env基因产物, 人免疫缺陷病毒(env Gene Products, Human Immunodeficiency Virus)
DOI
10.1038/s41591-018-0042-6
PMID
29867235
发布时间
2024-06-15
- 浏览14
Nature medicine
Nature medicine
857-867页
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