ERK1/2 MAPK promotes autophagy to suppress ER stress-mediated apoptosis induced by cadmium in rat proximal tubular cells.

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作者： Tongwang,Luo ^[1] ; Huiyan,Zhang ^[1] ; Qi,Yu ^[1] ; Gang,Liu ^[1] ; Mengfei,Long ^[1] ; Kanglei,Zhang ^[1] ; Wei,Liu ^[1] ; Ruilong,Song ^[1] ; Jianchun,Bian ^[1] ; Jianhong,Gu ^[1] ; Hui,Zou ^[1] ; Xuezhong,Liu ^[1] ; Yan,Yuan ^[2] ; Zongping,Liu ^[3]

作者单位： College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road,Yangzhou 225009, China; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China; Jiangsu Key Laboratory of Zoonosis,Yangzhou, China. ^[1] College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road,Yangzhou 225009, China; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China; Jiangsu Key Laboratory of Zoonosis,Yangzhou, China. Electronic address: yuanyan@yzu.edu.cn. ^[2] College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road,Yangzhou 225009, China; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China; Jiangsu Key Laboratory of Zoonosis,Yangzhou, China. Electronic address: liuzongping@yzu.edu.cn. ^[3]

关键词 Apoptosis Autophagy Cadmium ER stress ERK1/2

主题词动物(Animals);细胞凋亡(Apoptosis);自噬(Autophagy);镉(Cadmium);细胞, 培养的(Cells, Cultured);上皮细胞(Epithelial Cells);肾小管, 近端(Kidney Tubules, Proximal);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction)

DOI 10.1016/j.tiv.2018.06.001

PMID 29870746

发布时间 2018-11-26

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Toxicology in vitro

2018年52卷

60-69页

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ERK1/2 MAPK promotes autophagy to suppress ER stress-mediated apoptosis induced by cadmium in rat proximal tubular cells.

Toxicology in vitro

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Toxicology in vitro

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ERK1/2 MAPK promotes autophagy to suppress ER stress-mediated apoptosis induced by cadmium in rat proximal tubular cells.

Toxicology in vitro

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Toxicology in vitro

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