Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice.

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第一作者： Giorgio,Bergamini

第一单位： Preclinical Laboratory for Translational Research into Affective Disorders, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Switzerland.

作者： Giorgio,Bergamini ^[1] ; Jonas,Mechtersheimer ^[2] ; Damiano,Azzinnari ^[3] ; Hannes,Sigrist ^[1] ; Michaela,Buerge ^[1] ; Robert,Dallmann ^[3] ; Robert,Freije ^[1] ; Afroditi,Kouraki ^[1] ; Jolanta,Opacka-Juffry ^[3] ; Erich,Seifritz ^[4] ; Boris,Ferger ^[5] ; Tobias,Suter ^[6] ; Christopher R,Pryce ^[6]

作者单位： Preclinical Laboratory for Translational Research into Affective Disorders, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Switzerland. ^[1] Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Switzerland. ^[2] Neuroscience Center Zurich, University of Zurich and ETH Zurich, Switzerland. ^[3] Warwick Medical School, University of Warwick, Coventry, United Kingdom. ^[4] Brains On-line, Groningen, The Netherlands. ^[5] Department of Life Sciences, University of Roehampton, London, UK. ^[6] Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Switzerland. ^[7] CNS Diseases Research Germany, Boehringer Ingelheim Pharma GmbH & Co. KG., Biberach, Germany. ^[8] Neuroimmunology and MS Research, Neurology, and Clinical Research Priority Program Multiple Sclerosis, University Hospital Zurich, University of Zurich, Switzerland. ^[9]

关键词 Depression Immune activation Mesolimbic dopamine system Mouse model Reward Social stress

DOI 10.1016/j.ynstr.2018.01.004

PMID 29888303

发布时间 2020-09-30

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Neurobiology of stress

2018年8卷

42-56页

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Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice.

Neurobiology of stress

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Neurobiology of stress

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Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice.

Neurobiology of stress

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Neurobiology of stress

相关期刊

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