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Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.

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第一作者： Franziska,Bleichert

第一单位： Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland; franziska.bleichert@fmi.ch mbotchan@berkeley.edu jmberger@jhmi.edu.

作者： Franziska,Bleichert ^[1] ; Alexander,Leitner ^[2] ; Ruedi,Aebersold ^[3] ; Michael R,Botchan ^[4] ; James M,Berger ^[5]

作者单位： Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland; franziska.bleichert@fmi.ch mbotchan@berkeley.edu jmberger@jhmi.edu. ^[1] Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland. ^[2] Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.;Faculty of Science, University of Zurich, 8057 Zurich, Switzerland. ^[3] Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720; franziska.bleichert@fmi.ch mbotchan@berkeley.edu jmberger@jhmi.edu. ^[4] Department of Biophysics and Biophysical Chemistry, Johns Hopkins School of Medicine, Baltimore, MD 21205 franziska.bleichert@fmi.ch mbotchan@berkeley.edu jmberger@jhmi.edu. ^[5]

关键词 AAA+ ATPase DNA replication helicase loading initiators origin recognition complex