Fasudil preserves lung endothelial function and reduces pulmonary vascular remodeling in a rat model of end‑stage pulmonary hypertension with left heart disease.
作者:
主题词
1-(5-异喹啉磺酰基)-2-甲基哌嗪(1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine);动物(Animals);心脏扩大(Cardiomegaly);细胞系(Cell Line);心脏病(Heart Diseases);人类(Humans);高血压, 肺性(Hypertension, Pulmonary);肺(Lung);男(雄)性(Male);肌细胞, 平滑肌(Myocytes, Smooth Muscle);肺动脉(Pulmonary Artery);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);rho相关激酶类(rho-Associated Kinases);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)
DOI
10.3892/ijmm.2018.3728
PMID
29901088
发布时间
2018-11-14
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