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A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain.

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第一作者： Kristofer,Davie

第一单位： VIB Center for Brain & Disease Research, KU Leuven, Leuven 3000, Belgium; Department of Human Genetics KU Leuven, Leuven 3000, Belgium.

作者： Kristofer,Davie ^[1] ; Jasper,Janssens ^[1] ; Duygu,Koldere ^[1] ; Maxime,De Waegeneer ^[1] ; Uli,Pech ^[2] ; Łukasz,Kreft ^[3] ; Sara,Aibar ^[1] ; Samira,Makhzami ^[1] ; Valerie,Christiaens ^[1] ; Carmen,Bravo González-Blas ^[1] ; Suresh,Poovathingal ^[4] ; Gert,Hulselmans ^[1] ; Katina I,Spanier ^[1] ; Thomas,Moerman ^[5] ; Bram,Vanspauwen ^[6] ; Sarah,Geurs ^[7] ; Thierry,Voet ^[7] ; Jeroen,Lammertyn ^[6] ; Bernard,Thienpont ^[7] ; Sha,Liu ^[2] ; Nikos,Konstantinides ^[8] ; Mark,Fiers ^[2] ; Patrik,Verstreken ^[2] ; Stein,Aerts ^[9]

作者单位： VIB Center for Brain & Disease Research, KU Leuven, Leuven 3000, Belgium; Department of Human Genetics KU Leuven, Leuven 3000, Belgium. ^[1] VIB Center for Brain & Disease Research, KU Leuven, Leuven 3000, Belgium; Department of Neurosciences, KU Leuven, Leuven 3000, Belgium. ^[2] VIB Bioinformatics Core, VIB, Ghent 9052, Belgium. ^[3] VIB Center for Brain & Disease Research, KU Leuven, Leuven 3000, Belgium. ^[4] ESAT, KU Leuven, Leuven 3001, Belgium; Smart Applications and Innovation Services, IMEC, Leuven 3001, Belgium. ^[5] Department of Biosystems, KU Leuven, Leuven 3001, Belgium. ^[6] Department of Human Genetics KU Leuven, Leuven 3000, Belgium. ^[7] Department of Biology, New York University, New York, NY 10003, USA. ^[8] VIB Center for Brain & Disease Research, KU Leuven, Leuven 3000, Belgium; Department of Human Genetics KU Leuven, Leuven 3000, Belgium. Electronic address: stein.aerts@kuleuven.vib.be. ^[9]

关键词 Drosophila aging brain gene regulatory networks mitochondria neuronal subtypes oxidative phosphorylation single-cell RNA-seq single-cell bioinformatics