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Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study.

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第一作者： Andrew,Conway Morris

第一单位： University Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Box 93, Hills Road, Cambridge, CB2 0QQ, England, UK. mozza@doctors.org.uk.;MRC Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, UK. mozza@doctors.org.uk.

作者： Andrew,Conway Morris ^[1] ; Deepankar,Datta ^[2] ; Manu,Shankar-Hari ^[3] ; Jacqueline,Stephen ^[4] ; Christopher J,Weir ^[4] ; Jillian,Rennie ^[5] ; Jean,Antonelli ^[4] ; Anthony,Bateman ^[6] ; Noel,Warner ^[7] ; Kevin,Judge ^[7] ; Jim,Keenan ^[7] ; Alice,Wang ^[8] ; Tony,Burpee ^[9] ; K Alun,Brown ^[10] ; Sion M,Lewis ^[10] ; Tracey,Mare ^[10] ; Alistair I,Roy ^[11] ; Gillian,Hulme ^[12] ; Ian,Dimmick ^[12] ; Adriano G,Rossi ^[5] ; A John,Simpson ^[13] ; Timothy S,Walsh ^[2]

作者单位： University Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Box 93, Hills Road, Cambridge, CB2 0QQ, England, UK. mozza@doctors.org.uk.;MRC Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, UK. mozza@doctors.org.uk. ^[1] MRC Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, UK.;Edinburgh Critical Care Research Group, University of Edinburgh School of Clinical Sciences, Edinburgh, Scotland, UK. ^[2] Intensive Care Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, London, England, UK. ^[3] Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK. ^[4] MRC Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, UK. ^[5] Intensive Care Unit, Western General Hospital, Crewe Road South, Edinburgh, Scotland, UK. ^[6] BD Biosciences, San Jose, CA, USA. ^[7] BD Biosciences, San Jose, CA, USA.;IncellDx, Menlo Park, CA, USA. ^[8] Applied Cytometry, Sheffield, England, UK. ^[9] Vascular Immunology Research Laboratory, Rayne Institute (King's College London), St Thomas' Hospital, London, England, UK. ^[10] Integrated Critical Care Unit, Sunderland Royal Hospital, Sunderland, England, UK. ^[11] Flow Cytometry Core Facility Laboratory, Faculty of Medical Sciences, Centre for Life, Newcastle University, Newcastle, England, UK. ^[12] Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, England, UK. ^[13]

关键词 Cross infection Immunoparesis Immunophenotyping Monocytes Neutrophils T-lymphocytes, regulatory