The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants.

导出 OA

翻译打印收藏纠错

作者： Jimin,Yuan ^[1] ; Wan Hwa,Ng ^[1] ; Paula Y P,Lam ^[1] ; Yu,Wang ^[2] ; Hongping,Xia ^[1] ; Jiajun,Yap ^[1] ; Shou Ping,Guan ^[1] ; Ann S G,Lee ^[1] ; Mei,Wang ^[3] ; Manuela,Baccarini ^[4] ; Jiancheng,Hu ^[5]

作者单位： Division of Cellular and Molecular Research, Singapore, Singapore. ^[1] Cancer and Stem Cell Program, Duke-NUS Medical School, 8 College Road, 169857, Singapore, Singapore. ^[2] Division of Medical Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore, 169610, Singapore. ^[3] Office of Clinical & Academic Faculty Affairs, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore. ^[4] Department of Physiology, National University of Singapore, 2 Medical Drive, 117597, Singapore, Singapore. ^[5] Max F. Perutz Laboratories, University of Vienna, Doktor-Bohr-Gasse 9, 1030, Vienna, Austria. ^[6] Division of Cellular and Molecular Research, Singapore, Singapore. hu.jiancheng@nccs.com.sg. ^[7] Cancer and Stem Cell Program, Duke-NUS Medical School, 8 College Road, 169857, Singapore, Singapore. hu.jiancheng@nccs.com.sg. ^[8]